Top Ten Reexamination and Invalidation Cases
Interpreting the Stereochemistry of Phosphorus and Proving Commercial Success: How Gilead's Nucleoside Phosphoramidate Prodrug Patent "Captured" Sofosbuvir and Survived Invalidation
9 November 2026In pharmaceutical patent disputes, claim interpretation can be decisive because it defines the claimed subject matter against which novelty and inventive step are assessed. A single stereochemical notation in a structural formula may determine whether a patented claim covers a commercially successful drug worth billions of dollars. The dispute in the Gilead Sciences Inc. (hereinafter […]
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